Mario Gimona

Address: Unit of Actin Cytoskeleton Regulation
Consorzio Mario Negri Sud
Department of Cell Biology and Oncology
Via Nazionale 8A
66030 Santa Maria Imbaro
Phone: +39 0872 570 293
Fax: +39 0872 570 412

Research Interests

Research activities in my laboratory focus on the molecular mechanisms that drive stability and dynamic modulation of the actin cytoskeleton. The laboratory capitalizes on the combinatorial use of protein chemical, molecular biological, microscopic, and cell biological techniques. We study the induction of actin cytoskeleton rearrangement, focal adhesion disassembly, and the spatially and temporally restricted inhibition of contractile forces that lead to the Src-dependent formation of podosomes in vascular smooth muscle cells.